不同负荷运动训练对大鼠骨骼肌线粒体三羧酸循环的影响及其机制研究     

李洁  杨静  赵丽丽 《武汉体育学院学报》2019,53(5):88-94

目的：探讨不同负荷运动训练对大鼠骨骼肌线粒体三羧酸循环的影响及其机制。方法：将雄性Wistar大鼠50只随机均分为5组：安静对照组（C）、低负荷运动训练组（LT）、中等负荷运动训练组（MT）、高负荷运动训练组（HT）和极高负荷运动训练组（ST），每组10只。各运动组分别进行6周的跑台运动训练。训练方案结束后，取腓肠肌样本，提取线粒体，测定线粒体柠檬酸合成酶（CS）、异柠檬酸脱氢酶（ICD）和α-酮戊二酸脱氢酶（α-KGDHC）活性；线粒体Ga²⁺含量、胞浆NADH、NAD⁺、ATP和ADP含量，以及ICD mRNA转录水平。结果：（1）不同负荷运动训练组线粒体CS、ICD和α-KGDHC的活性均显著高于安静对照组（P < 0.01），且CS和ICD活性由高到低顺序均为：MT组 > HT组 > ST组 > LT组 > C组，α-KGDHC活性由高到低顺序为：HT组 > MT组 > ST组 > LT组 > C组。（2）不同负荷运动训练组线粒体Ca²⁺ 含量均显著高于安静对照组（P < 0.01），其含量由高到低顺序为：MT组 > HT组 > ST组 > LT组 > C组；胞浆NADH/NAD⁺和ATP/ADP的比值均显著低于安静对照组（P < 0.01），其比值由低到高顺序为：MT组 < ST组 < HT组 < LT组 < C组。（3）不同负荷运动训练组ICD mRNA转录水平均高于安静对照组（P < 0.01），其水平由高到低顺序为： MT组 > HT组 > ST组 > LT组 > C组。结论：低负荷、中等负荷、高负荷及极高负荷运动训练均可提高大鼠骨骼肌线粒体三羧酸循环功能，且中等负荷运动训练效果最佳。其机制与胞浆NADH/NAD⁺和ATP/ADP比值、线粒体摄钙能力及限速酶基因的表达有关。  相似文献   

国内外社交媒体存档研究与实践述评     

黄新荣  高晨翔 《图书情报工作》2019,63(4):122-134

[目的/意义]社交媒体是网络信息资源的重要组成部分，对国内外社交媒体存档的相关研究成果进行总结与梳理，形成比较完整的综述内容，为国内该领域研究提供参考与借鉴。[方法/过程]基于多学科视角，通过文献计量与内容分析得到社交媒体存档领域的文献分布情况，总结社交媒体存档的理论基础，从宏观层面将社交媒体存档理论与实践研究归纳为"目的与主体""政策与指南""问题与障碍"三个研究主题并展开综述。[结果/结论]国内外社交媒体存档研究具有发展速度较快、与实践结合紧密、区域发展不均衡等特征，在未来研究中需要重视研究对象的变化、管理标准的构建以及多主体间的协作。最后对国内社交媒体存档研究与实践的发展提出建议。  相似文献   

平行/重合D膜超势，Ooguri-Vafa不变量与类型II弦理论/F理论对偶     

蒋笑添  杨富中 《中国科学院大学学报》2019,36(5):590-597

利用类型Ⅱ弦理论/F理论对偶，第一次在平行和重合相区计算一个具体的双D膜系统的超势，并提取Ooguri-Vafa不变量。平行D膜相与重合D膜相间的相变也对应着D膜世界叶上规范理论规范对称性的提升U（1）×…×U（1）→U（n）。计算显示这两个相区的超势截然不同，并给出不同的Ooguri-Vafa不变量。这意味着相变的发生导致两个相区能谱结构的差异。  相似文献   

灰色预测法在情报研究中的应用研究综述     

张晶晶  李泽霞 《图书情报工作》2021,64(24):106-114

[目的/意义] 灰色预测法可有效处理情报研究中广泛存在的小样本数据，通过对灰色预测法在情报研究中的应用情况进行梳理，总结其在应用过程中存在的不足，为灰色预测法在情报研究中的进一步应用提供参考。[方法/过程] 通过综述情报研究中涉及灰色预测法的相关文献，从数据选取、模型构建和解决的问题等方面对情报研究中灰色预测法的应用进行概述，总结当前情报研究中灰色预测法的应用所存在的问题，并提出改进建议。[结果/结论] 在方法应用上，已有研究主要采用数列灰预测，且模型集中在单变量灰色预测模型，根据预测对象不同，灰色预测法已经在包括期刊分析、图书馆运行管理、热点主题分析及科研机构评价方面得到了很好的应用，未来可根据预测对象特点及研究目标尝试不同的灰色预测方法，扩宽灰色预测法在其他方面的情报研究问题中的应用。  相似文献   

Understanding the relative contribution of technical and tactical performance to match outcome in Australian Football     

Christopher M Young  Wei Luo  Paul B Gastin  Daniel B Dwyer 《Journal of sports sciences》2020,38(6):676-681

ABSTRACT

The aim of this study was to assess if tactical and technical performance indicators (PIs) could be used in combination to model match outcomes in Australian Football (AF). A database of 101 technical PIs and 14 tactical PIs from every match in the 2009–2016 Australian Football League (AFL) seasons was merged. Two outcome measures Win-loss and Score margin were used as dependent variables. The top 45 ranked technical and tactical PIs from a feature selection process were used to model match outcome using decision tree and Generalised Linear Models (GLMs). Of the top 45 selected features, this included seven tactical PIs. The Win-loss-based Decision tree model achieved a classification accuracy of 89.0% and GLM 93.2%. A Score margin-based GLM achieved a root mean squared error (RMSE) of 6.9 points. A combined approach to the classification of match outcomes provided no improvement in model accuracy compared with previous literature. However, this study has established the relative importance of technical and tactical measures of performance in relation to successful team performance in AF.  相似文献   

Press Credentials and Hybrid Boundary Zones: The Case of WorldNetDaily and the Standing Committee of Correspondents     

Jordan M. Foley 《Journalism Practice》2020,14(8):933-953

ABSTRACT

Press credentialing practices are a vital, yet understudied site of scholarly research on journalistic norms and practices. Press credentialing not only structures internal professional hierarchies, but they also signify the boundaries of the journalistic field itself. This paper explores the legal and theoretical implications of press credentialing to cover the United States Congress, drawing on the concepts of boundary work and journalistic authority to demonstrate the material impact of the space between fields on professional legitimation in journalism. Using WorldNetDaily (WND) as a case study, I argue that the Standing Committee of Correspondents (SCC) occupies a hybrid boundary zone between the journalistic and political fields, generating a unique tension in First Amendment jurisprudence that places journalists in a paradoxical role as both the professional embodiments of free speech and its constitutional steward. The resulting jurisdictional conflict between the SCC and WND extends the relational model of journalistic authority by articulating how journalist-state relations can fundamentally augment the process of legitimation at its fuzzy boundaries. The relevance and implications for press credentialing practices in the digital age are discussed.  相似文献   

面向智慧知识服务的科技文献大数据体系建设     

吴振新  钱力  谢靖  常志军  许丽媛  赵艳 《图书情报工作》2021,64(24):63-72

[目的/意义] 探索构建文献情报大数据知识资源体系，支撑面向多领域的智慧知识服务。[方法/过程] 基于AI应用需求，借鉴业界经验，梳理现有资源体系的问题，从多层次多维度扩展资源体系；构建可靠数据处理流程和计算平台，支持高效数据采集和处理；研发智能化数据治理工具，实现知识资源的有效治理，确保提供高质量数据资源。[结果/结论] 已初步形成覆盖多类型、多学科的科技文献大数据知识资源体系，构建完成高度自动化的数据采集治理流程，实施多重数据质量控制，积累数亿高质量数据，且为多个知识服务提供数据支撑。  相似文献   

Student success pocket-graphic: a mountain of data transformed     

Karen Briere  Kelly Drifmeyer 《Public Services Quarterly》2020,16(1):48-58

Abstract

How does a small community college library, without marketing experience or budget, advocate for its value to a campus community and its administrators? We did so by creating an engaging, bright, and easy-to-read “pocket-graphic.” In this column, we reflect on the process of shaping a multi-use product out of a mountain of data. Through research in design practices, field observations of popular information tools, and an uncomfortable step into braggadocio, we learned to articulate the successes of our library. Our “pocket-graphic” told our story, yes – but it also provoked surprise, questions (“you really have all that?”) and delight in the lesser known successes (“you really DO all that!”). In the process, we connected our students more deeply to helpful services and resources, faculty to supportive instruction, and positively changed the tone of conversation with all our stakeholders. By turning data points into selling points, we found insights and a focus that moved our own development forward, helping ourselves to define improved priorities for advancing our critical role in student success.  相似文献   

睡美人文献识别方法研究进展     

宗张建 《图书情报工作》2019,63(16):132-142

[目的/意义]睡美人文献是一类蕴藏着巨大科学价值的文献。对国内外睡美人文献识别方法的相关研究成果进行总结与梳理，形成比较完整的综述内容，为国内该领域研究提供参考与借鉴。[方法/过程]按方法属性将识别方法总结为4类，概括各识别方法的基本思路、识别标准、优点及局限性，并参照睡美人文献识别方法的4条原则进行对比，指出各识别方法的适用范围。[结果/结论]睡美人文献识别方法已由单一逐渐丰富，从主观参数向客观指标演变，从单一引文曲线向多种形式曲线并用发展。未来睡美人文献识别研究可从睡眠深度标准再定义、识别方法再组合上深入。此外，还需重视睡美人文献的定性研究和识别方法的验证性研究，重视睡美人引文价值的测度以及预测性研究。  相似文献   

Online visibility of software-related web sites: The case of biomedical text mining tools     

Gael Pérez-Rodríguez  Martín Pérez-Pérez  Florentino Fdez-Riverola  Anália Lourenço 《Information processing & management》2019,56(3):565-583

  相似文献